Summary
With the ongoing trend of cannabis legalization in the United States and across the world, there is a critical need to better understand links between cannabis use, brain development, and cognitive-behavioral outcomes. Despite growing public belief that cannabis use is relatively benign, there remains a dearth of large longitudinal studies examining cannabis use and brain development in humans. We propose to leverage three large multimodal neuroimaging datasets, spanning preadolescence to late adulthood: ABCD (n=11,880; ages 9-20 followed longitudinally), IMAGEN (n=2,400; ages 14-23, followed
