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Does age matter for the development of pathogenic T helper 2 resident memory cells in the lung?

US National Institute of Allergy and Infectious Diseases grant open #nih-5R21AI180866-02

Summary

PROJECT SUMMARY Allergic asthma is a chronic inflammatory disease that often progresses from childhood to adulthood. Approximately 8% of the world population suffer from allergic asthma, making it one of the most common respiratory diseases. Allergic asthma is characterized by recurrent type 2 inflammation, mucus hyperplasia, and airway hyperreactivity. Current treatment strategies aim to temporally alleviate the symptoms of asthma attack and have no beneficial effect on disease progression. Recent studies have identified pathogenic T helper 2 resident memory cells in the lung (Th2-TRMs) as th

Does age matter for the development of pat…
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