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Harnessing the peptide code of bilingual biopolymers to control assembly and RNA localization

US NSF grant open #nsf-2532420

Summary

NON-TECHNICAL SUMMARY: Nucleic acids and proteins are both incredibly powerful in their ability to encode information and perform specific functions, yet they each benefit from unique advantages with regard to designability and breadth of function. To date, synthetic polymers seeking to mimic these natural biopolymers only take advantage of a single code – either nucleic acid or protein. The proposed work explores "bilingual biopolymers" as a novel class of biomolecules that are able to simultaneously encode both nucleic acid and protein information, in turn providing greater control over s

Harnessing the peptide code of bilingual b…
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