Summary
Chromosomes carry genetic instructions that allow cells to grow, respond to the environment, and pass information to future generations. Just as the function of a protein is understood through its amino acid sequence, three-dimensional structure, and conformational dynamics, a complete understanding of chromosome function requires knowledge of DNA sequence, chromosome structure, and dynamic behavior. Modern sequencing and imaging methods have transformed the ability to read genomes and capture snapshots of chromosome architecture, but much less is known about how different regions of the chrom