Summary
ABSTRACT This comprehensive research program is focused on revolutionizing the treatment of Glioblastoma (GBM), a highly aggressive brain tumor that currently has limited and largely ineffective treatment options. GBM is known for its devastating impact on patients, often leading to poor prognosis and survival rates. The proposal brings together a multidisciplinary team of experts from various fields, all working towards a common goal - to significantly enhance the efficacy of Chimeric Antigen Receptor (CAR) T-cell therapy using innovative translational biomaterials. The team is driven by a ce