Summary
NON-TECHNICAL SUMMARY: Many promising new medicines fail to reach patients because they do not dissolve well in water, making it hard for the body to absorb them. This poor solubility affects over 90% of drugs in development, limiting treatment options, increasing costs, and often forcing researchers to abandon otherwise effective compounds. Polymeric micelles are tiny, self-assembled carriers made from long-chain molecules that offer a powerful way to encapsulate and deliver these hydrophobic drugs safely and efficiently. However, current designs often achieve only low drug loading, requir
