Summary
Antibodies are key proteins of the immune system that help fight disease. In people, immune cells called B cells create antibodies and then evolves them. B cells take months to do this, which makes it difficult to study antibody creation and evolution. This CAREER project will design a method to create and evolve antibodies “from scratch” in yeast, which will open new avenues for exploring antibody creation, evolution, and function. The results of the project will provide insights into the formulation of more effective disease-targeting therapeutics. The project will support project-based
