Summary
The current proposal aims to develop a for at-home-use neuroprosthesis for restoring brain-controlled functional hand grasping to Veterans and others living with chronic tetraplegia due to spinal cord injury (SCI). This system leverages and advances two established technologies – functional-electrical stimulation (FES) systems for re-animating paralyzed limbs, and intracortical brain-machine interfaces (BMIs) for recording and discerning motor intent. Our previous work successfully demonstrated a Veteran with chronic tetraplegia using a simple proof-of-concept FES+BMI system, composed of tempo