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Regulation of Myometrial Smooth Muscle Contractility by Mechanical Stretch and Mechanoinflammation

US NSF grant open #nsf-2527994

Summary

Many cells in the body, including muscle cells and immune cells, react to stretch. The myometrium is the smooth muscle layer of the uterus, the organ that supports the development of a fetus during a pregnancy. The goal of this research is to determine the impact of varying amounts of stretch on the contraction of muscle cells isolated from the human uterus, including identifying the parts of cells that respond to stretch and the influence of nearby immune cells. Project outcomes intend to include a deeper understanding of the impact of stretch on uterine contractions and the discovery of new

Regulation of Myometrial Smooth Muscle Con…
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