Summary
Summary Glycolysis, the fundamental metabolic process in which glucose is converted to lactate, lies at the core of diabetes and metabolic dysfunction, as well as cancer and immune function. Regulation of glycolytic rate by insulin and other endocrine signals is essential for bodily metabolic homeostasis and also plays important cell-intrinsic roles in regulating cellular proliferation, apoptosis, and differentiation. While there is a long history of quantitative modeling of glycolysis in bulk, regulation at the single-cell level has been explored in much less depth. This lack of understanding
