Summary
Organisms frequently rely upon cell-cell interactions to build various structures throughout their body plan. One outstanding example of this is the formation of the cranial trigeminal ganglion, a tissue that consists of neurons arising from both neural crest and placode cells. The central question of this research is to understand how trigeminal ganglion neurons coordinate, in space and time, their initial formation, and extension of axons to target tissues, to detect sensations. To address this question, an innovative, multidisciplinary approach will be taken that spans the single cell to wh