Summary
Project Summary/Abstract Due to improved treatment and supportive care, five-year survival rates for childhood cancer now exceed 85%. However, patients treated with anthracycline chemotherapy or chest-directed radiation have a dose-related risk for adverse cardiovascular sequelae, including cardiomyopathy, coronary artery disease and valvular heart disease, with a negative impact on quality of life and overall survival. Earlier recognition and interventions to manage cardiac morbidity among childhood cancer survivors (CCS) could provide opportunities to improve quality of remaining life. To fa
