Summary
Living cells use enzymes to perform numerous biological functions. These enzymes work on cellular targets which are extremely small in size, oftentimes measured at the nanometer (one billionth of a meter) length scale. This CAREER project aims to understand the fundamental mechanisms of how enzyme-sensitive, nanoscale materials interact with an enzyme. This goal will be realized by developing nanoparticles, which respond to a particular class of enzymes by changing particle size and function. Further, these particles will mimic the function of a naturally occurring, enzyme-sensitive protein –
