Summary
PROJECT SUMMARY/ABSTRACT – GENETICALLY ENGINEERED MOUSE MODELS SHARED RESOURCE The Genetically Engineered Mouse Models Shared Resource (GEMMSR), formerly the Transgenic Gene Knockout Shared Resource, provides St. Jude Comprehensive Cancer Center (SJCCC) members with convenient and economic access to generating genetically engineered mouse models (GEMMs). This includes the production of transgenic, knock-out, conditional knock-out, deletion, and knock-in mouse lines. These models are critical tools for advancing science at the SJCCC by elucidating the role of genetic changes in the initiation a