Summary
PROJECT SUMMARY Acute brain dysfunction (ABD) during sepsis occurs in 30% of children and is associated with a seven-fold increased risk of mortality. Survivors who experienced ABD during sepsis are more likely to have both functional morbidity and a reduction in health-related quality of life. However, there is a critical knowledge gap about the prevalence of new neurocognitive morbidities for sepsis survivors. With 100,000 children in the United States and 25 million children worldwide experiencing sepsis each year, new neurocognitive morbidities can have a lasting impact on their developmen