Summary
Despite significant public investment, innovations arising from early-stage discovery research often fails to reach the market, limiting their potential societal and economic impacts. While existing federal programs have improved aspects of the innovation pipeline, persistent systemic barriers remain. These translational "leaks" stem from complex challenges in technology transfer, commercialization pathways, inter-sector coordination, and a lack of appropriately targeted funding mechanisms. Addressing these gaps in the research-to-translation pipeline is critical to preventing promising discov
