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ISS: Biomanufacturing of Mesenchymal Stem Cell Secretomes for Tissue Regeneration

US NSF grant open #nsf-2529546

Summary

Mesenchymal stem cells (MSC) are a special type of cell that can reduce inflammation and help rebuild bone, cartilage, and other muscle and skeletal tissues. MSC can be grown and multiplied outside of the body for use as therapies, but the MSC lose their restorative abilities after being cultured for a long time or in tissues due to disease and aging. One possible cause for this decline is that MSC function is altered by physical forces, including interaction with growth supports and gravity. It is not well understood how physical forces change MSC pro- or anti-inflammatory strength. The goal

ISS: Biomanufacturing of Mesenchymal Stem …
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