Summary
The overarching goal of our CCHI application on “Vaccine and Infection Induced Immunity in the Young and Aged” is to address fundamental issues about innate and adaptive immunity in humans to infection and vaccination. Our proposal is focused around a large cohort of > 700 COVID-19 patients that we have been following for the past 3 years and now propose to follow for an additional 5 years during the course of this proposal. These patients were recruited at our two clinical research sites, Emory University (Atlanta, Georgia) and Fred Hutchinson Cancer Center (Seattle, Washington). Our combined
