Summary
Tumor tissues are usually harder than surrounding healthy tissues, leading to a different microenvironment for cancer cells inside. Since the behaviors and functions of cells are regulated by physical cues from their microenvironment, emerging research has suggested that the altered mechanics of tumor tissue plays a crucial role in the progression of metastatic cancers. To understand the relationship between the properties of the microenvironment and tumor growth, it is essential to quantify these mechanical properties with high spatial resolution in three dimensions. However, existing mechani