Summary
Project Summary The ability to precisely detect biomolecules and measure their dynamics is central to our understanding of the origins of debilitating diseases such as Alzheimer’s and Parkinson’s and is a prerequisite for designing more effective treatments. However, biomolecules are typically a few nanometers in size, which makes them difficult to observe with optical methods. One of the primary ways to overcome this challenge is to add labels, such as fluorescent tags, that make them visible. This has opened the field of single molecule analysis, with the significant advantages of allowing r