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Precision brain charts for imaging-genomics of schizophrenia and the psychosis spectrum

US National Institute of Mental Health grant open #nih-5R01MH133843-03

Summary

ABSTRACT An unmet need for psychiatric neuroimaging is a standard developmental frame of reference to benchmark studies of neurodevelopmental conditions such as schizophrenia the psychosis spectrum (PS). Using a modelling approach that has proven successful for non-imaging growth charts in clinical pediatrics, and in our preliminary work that was focused on a limited set of global brain MRI features, we propose to leverage data from our multi-site Brain Chart Consortium to produce computational charts of brain maturation for a far richer set of brain morphological features across anatomical sc

Precision brain charts for imaging-genomic…
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