Summary
The immune system plays a critical role in protecting the body from disease. However, in the context of cancer, the immune system becomes ineffective at recognizing and eliminating tumor cells. One important and often overlooked reason for this failure is that tumors pose not only biological but also physical challenges. As tumors grow, they generate crowding and pressure that physically squeeze nearby cells and disrupt how they function. With brain tumors, the skull limits how much the tissue can expand and amplifies these forces. This Faculty Early Career Development Program (CAREER) project
