Summary
This proposal introduces a new way to grow the bioeconomy by making useful products using biology without relying on living cells. These “cell-free systems” have the potential to lower costs and speed up the production of essential chemicals if the right biological tools, or proteins, exist in the first place. The research combines three advanced technologies to that end: computational design of thousands of proteins at once; a shelf-stable system to test, transport, and use the designed proteins; and new-to-nature building blocks that expand what these proteins can do beyond the limits of bas
