Summary
Extracellular vesicles naturally occur in biological fluids. These vesicles and their cargo are a promising source of biomarkers for personalized healthcare, including early cancer detection, health monitoring, and infectious disease. However, current methods for isolating and analyzing these particles are derived from cellular analysis methods, such as size-based sorting, biological targeting, or density-based isolation. For vesicles, these methods are often costly, time consuming, and produce inconsistent results. A key limitation is the poor understanding of vesicle mechanical properties, s