Summary
Project Abstract How the brain reinforces neural activity to drive learning is a fundamental question in neuroscience. Dopamine is a critical neuromodulator that shapes neural circuits during reinforcement learning by modifying synaptic connections that encode rewarding behaviors. However, the precise synaptic mechanisms by which dopamine-dependent plasticity sculpts behaviorally relevant cortical ensembles remain poorly understood. A major barrier to addressing this question has been the lack of experimental approaches that allow for real-time control of reinforcement signals while simultane
