Summary
PROJECT SUMMARY Bronchopulmonary dysplasia (BPD) is the most common complication affecting preterm neonates and is defined by supplemental oxygen dependence at 36 weeks postmenstrual age. Advances in neonatal care have improved overall survival of preterm neonates though BPD prevalence continues to increase. BPD develops after early-life lung injury caused by myriad pre- and postnatal factors such as the administration of supplemental oxygen. Though a lifesaving therapeutic intervention, high concentrations of oxygen (hyperoxia) arrest alveolarization and vascularization and induce inflammatio
