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The metabolic clock as a regulator of cell fate decision

US National Institute of General Medical Sciences grant open #nih-5R35GM155038-02

Summary

Project Summary: Our organs respond dynamically to changes in the body’s demands by adapting both their size and activity levels. In these processes, mechanisms governing cell fate decisions, which influence the equilibrium between cell death and cell proliferation, assume crucial roles. Although decades of research have revealed the involvement of cell cycle regulators, epigenetic modulators, metabolic pathways and ionic homeostasis in this complex decision process, we still have major gaps in our understanding of the mechanisms that govern cell fate. These gaps need to be addressed in order

The metabolic clock as a regulator of cell…
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