Summary
Project Summary Weight gain with Dolutegravir (DTG), an integrase strand transfer inhibitor (INSTI), has been observed in People living with HIV (PLHIV) including postpartum women. How DTG-based ART regimens affect postpartum weight is not known. Understanding the impact of maternal DTG-regimens on the physiology of postpartum body weight regulation has clinical significance as postpartum weight retention is known to increase future maternal risk of overweight, obesity and non-communicable diseases (NCD). DTG-based ART is being rolled as the first line regimen in Sub-Saharan Africa for HIV ma
