Summary
Proteins often target specific areas in the cell. Some reside exclusively inside the cell, some embed themselves in the cell wall, and some are tethered to the outside of the cell. Others are actively secreted. Designing therapeutic drugs or proteins must account for the location of the target protein. Many important targets, like viral proteins, are initially inside the cell. Developing proteins that can specifically recognize and bind to them inside a cell is challenging. The cell interior presents many competing molecular interactions due to crowding, protein aggregation, and local ionic co
