Summary
The U.S. population is aging, and millions are affected by neurodegenerative disorders, yet their causes remain largely unknown. Emerging research suggests that the gut microbiota plays a role in neurodegenerative processes by influencing brain pathophysiology. However, the mechanisms behind this microbiota-gut-brain axis (MGBA) are still poorly understood. Current studies of neurodegenerative diseases rely on animal models and clinical trials, which face major limitations such as ethical concerns, high costs, low throughput, and significant time and labor demands. Hence, it is essential to de
