Summary
Diagnostic testing is challenging when the targeted compounds are present in extremely small amounts. Sophisticated laboratories are required to detect low levels in samples, which makes the tests expensive and limits their availability. If the signal from targeted compounds could be amplified, some tests could become available in homes and smaller clinics. This project will make detection easier by amplifying signals using simple chemical reactions. The project will demonstrate that one chemical reaction can generate several new reactive molecules, which can then trigger more reactions. As