Summary
Excessive binge alcohol intake is a well-recognized risk factor for atrial fibrillation (AF), the most common arrhythmia with a high morbidity and mortality, yet current therapies have suboptimal effectiveness. [While aging is an unavoidable AF risk factor, alcohol as a secondary stressor exacerbates AF risk in the aging population.] Clinical data suggest that one-third of all new-onset AF cases are related to alcohol intoxication and alcohol abuse brings a high AF risk even in people without co-existing cardiovascular diseases. It is a classic concept that enhanced inflammation contributes to
