Summary
Summary Despite advances in tobacco smoking cessation interventions (pharmacological and behavioral), most smokers do not succeed at quitting, creating a major public health burden. Stress is one of the most commonly reported precipitants of tobacco craving and relapse. Tobacco withdrawal is associated with escalation of negative affect symptoms; our research has found multiple stress-related physiological and hormonal alterations during withdrawal that predict relapse. Modifying these stress-related biobehavioral changes may prove useful in reducing effects of stress. Cannabidiol (CBD) is a p
