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Showing 25 / 20086 · page 26/804
Hospital adaptation and resiliency for infected and uninfected patients during respiratory viral surge events: from seasonal influenza to COVID-19
US · PA NIH · grant
Project Summary / Abstract My long-term career goal is to become a leading independent investigator developing and evaluating surveillance, preparedness, and operations response strategies to combat the public health burdens from respirator…
Posted May 21, 2026
A Family-Based Digital Intervention to Address Early Substance Use Among Adolescents in Primary Care Settings
US National Institute on Drug Abuse · grant
This proposal seeks to develop and evaluate a novel tailored family-based videogame, FamilyBond (FamB), to prevent increases in substance misuse among mid-adolescents with early substance use in primary care settings. Over six million adole…
Posted May 21, 2026
The Impact of Positive Airway Pressure (PAP) Therapy on Myocardial Blood Flow in Adults with Obstructive Sleep Apnea at High-Risk of Cardiovascular Disease: The PAP-Flow Study
US National Heart Lung and Blood Institute · grant
ABSTRACT New and innovative approaches to studying modifiable mechanisms of heart failure are crucial. Heart failure impacts approximately 7 million adults in the United States and has a 5-year mortality rate of 42%. Obstructive sleep apnea…
Posted May 21, 2026
REACH Center Administrative Core
US · IL NIH · grant
PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core aims to promote relevant research through funding and coordination of the Developmental Core, Community Engagement Core, and Exposure Assessment Core. The Administrative Core …
Posted May 21, 2026
Cancer Prevention and Control Training Program
US National Cancer Institute · grant
We propose renewal of the University of Alabama at Birmingham (UAB) Cancer Prevention and Control Training Program T32 training grant. Our training program is the only one in the Deep South (Louisiana, Mississippi, Alabama, Georgia, South C…
Posted May 21, 2026
An integrated exercise and bladder training intervention to reduce falls in older women with urinary incontinence
US · IL NIH · grant
Project Summary/Abstract Urgency urinary incontinence (UUI) is a biomarker of falls risk and disproportionately affects older minority women living in urban communities. Over 50% of an estimated 10 million women age 70 and older with UUI wi…
Posted May 21, 2026
T cell Contributions to Neointima Formation in Pulmonary Hypertension
US National Heart Lung and Blood Institute · grant
Pulmonary Hypertension (PH) is a fatal disease where abnormal cells termed “neointima” progressively occlude the pulmonary arteries leading to debilitating right heart failure. PH pathology is characterized by perivascular inflammation, inc…
Posted May 21, 2026
Small-Molecule Covalent E6 Antagonists for Treatment of HPV Infection
US National Cancer Institute · grant
ABSTRACT “High-risk” human papillomavirus (HPV) types such as 16 (HPV-16) are identified in the majority of HPV- associated pre-malignant and malignant pathologies of cervical, anogenital, and oropharyngeal epithelia. The E6 protein is esse…
Posted May 21, 2026
Development of multinuclear MRI for image guided therapy of glioma patients
US · IL NIH · grant
7. Project Summary/Abstract Gliomas have a low survival rate of 36% at five-years, half the average survival rate across all cancers according to the last SEER and CBTRUS reports. Malignant brain tumors cause on average 20 years of potentia…
Posted May 21, 2026
Development of next generation 2HG and metabolic MR imaging for precision oncology of mutant IDH and wildtype glioma patients
US National Cancer Institute · grant
7. Project Summary/Abstract Gliomas are rarely curable tumors with a low survival rate of 36% at five-years that is well below the average survival rate of 67.2% across all cancers, according to SEER and CBTRUS. Malignant brain tumors cause…
Posted May 21, 2026
Bridges to the Baccalaureate Research Training Program at Howard University and Baltimore City Community College
US National Institute of General Medical Sciences · grant
The Bridges to Baccalaureate (B2B) Research Training Program at Howard University and Baltimore City Community College (BCCC) aims to create a novel, structured pathway for currently and formerly incarcerated individuals to pursue STEM care…
Posted May 21, 2026
The cellular molecular regulation of differing mechanisms of insulin resistance.
US · IL NIH · grant
Project Summary Molecular & Genetic Problem: Lipid-induced hepatic insulin resistance is due to diacylglyceride (DAG)-induced protein kinase C epsilon (PKCε) activation leading to inhibition of insulin receptor tyrosine kinase [4, 5]. Howe…
Posted May 21, 2026
Cell Identity and Signaling (CIS)
US National Cancer Institute · grant
Cell Identity and Signaling (CIS) Research Program Project Summary The key scientific goals of the Cell Identity and Signaling (CIS) Research Program are to advance discovery of novel molecular mechanisms of cell identity and cell signali…
Posted May 21, 2026
A sensitivity analysis framework for generalizing randomized clinical trial results in the presence of unmeasured treatment effect modifiers
US National Cancer Institute · grant
ABSTRACT Randomized controlled trials (RCTs) are the gold standard for assessing interventions for preventing and treating cancer, but their external validity is only guaranteed if the trial participants are a random sample from the target …
Posted May 21, 2026
The Michigan Department of Agriculture and Rural Development (MDARD) Animal Food Program (AFP) Animal Feed Regulatory ProgramStandards (AFRPS) Maintenance Track
US · MI Michigan Department of Agriculture and Rural Development (MDARD) Animal Feed Program (AFP) · grant
The Michigan Department of Agriculture and Rural Development (MDARD) Animal Feed Program (AFP) will enhance animal feed safety through the Animal Food Regulatory Program Standards (AFRPS) Maintenance Track. The AFRPS cooperative agreement w…
Posted May 21, 2026
Elucidating the causal associations underlying Alzheimer's disease
US National Institute on Aging · grant
Project Summary Alzheimer’s disease (AD) is a global crisis facing the aging population and society as a whole. With the number of people living with AD predicted to rise dramatically in the coming decades, it is imperative to pursue resear…
Posted May 21, 2026
B cell Response to Respiratory Viruses
US National Institute of Allergy and Infectious Diseases · grant
The B cell Immunobiology Section has evaluated the B cell response in multiple human Phase I clinical trials with experimental influenza vaccines conducted at the Vaccine Research Center with the goal of evaluating the magnitude and quality…
Posted May 21, 2026
Nicotinic Modulation of the Cognitive Control System in Late-Life Depression
US National Institute of Mental Health · grant
PROJECT SUMMARY: Deficits in cognitive control are core features of late-life depression, contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detection, and working memory. Clinically cha…
Posted May 21, 2026
Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS).
US National Institute of Neurological Disorders and Stroke · grant
ABSTRACT Columbia University, Clene, and Synapticure are partnering and taking an innovative approach to provide persons living with amyotrophic lateral sclerosis ALS (pALS) across all 50 states— including those in remote/rural areas—access…
Posted May 21, 2026
Novel tools for measuring typhoid vaccine impact
US · IL NIH RePORTER · grant
Project Summary Typhoid fever is a leading cause of invasive bacterial illness and death worldwide, with the majority of infections occurring in low- and middle-income countries where water and sanitation infrastructure is poor. Highly anti…
Posted May 21, 2026
Strategies for tuberculosis control in prisons
US National Institute of Allergy and Infectious Diseases · grant
Project Summary Tuberculosis remains one of the leading causes of death worldwide, despite the widespread availability of effective treatment and prevention measures. Prisons harbor among the highest rates of tuberculosis worldwide, and, in…
Posted May 21, 2026
Mentoring patient-oriented translational research in tuberculosis
US National Institute of Allergy and Infectious Diseases · grant
Project Summary Tuberculosis remains one of the leading causes of death worldwide, despite the widespread availability of effective treatment and prevention measures. To accelerate progress in reducing the global burden of tuberculosis, the…
Posted May 21, 2026
The MIGHT Trial - An Exploratory Clinical Trial of IVIG in anti-HMGCR ImmuneMediated Necrotizing Myopathy
US · IL NIH · NAICS 541714 · grant
PROJECT SUMMARY Anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) immune mediated necrotizing myopathy (IMNM) is an increasingly recognized, severe subset of autoimmune myopathy that causes significant muscle weakness, morbidity, and o…
Posted May 21, 2026
Data Core
US · IL Columbia Alzheimer’s Disease Research Center (NIH RePORTER) · grant
Project Summary The Database Management and Statistical (DMS) Core of the Columbia Alzheimer’s Disease Research Center formalizes and expands central data management and biostatistical resources and functions that have existed since the …
Posted May 21, 2026
Path B NDA's Continued Implementation of FDA's Produce Safety Rule in Nebraska
US Food and Drug Administration · grant
NDA’s Continued Implementation of FDA’s Produce Safety Rule in Nebraska-Path B PAR-21-174 Summary/Abstract The Nebraska Department of Agriculture Produce Safety Program (NDA PSP) will be pursuing Path B for this grant application to build…
Posted May 21, 2026