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Showing 25 / 20086 · page 33/804
Sensory Motor Transformations in Human Cortex
US · IL NIH · grant
Abstract: The long-term objective of this application is to understand cortical processing of sensory to motor transformations within the human cerebral cortex. A vast number of computations must be performed to achieve sensory-guided motor…
Posted May 21, 2026
Visuomotor Prosthetic for Paralysis
US National Eye Institute · grant
The objective of the proposed research is to obtain scientific knowledge of visuomotor transformations in posterior parietal cortex (PPC) and primary motor cortex (M1) from tetraplegic subjects in a clinical trial to advance the development…
Posted May 21, 2026
Center for Viral Systems Biology (CViSB)
US National Institute of Allergy and Infectious Diseases · grant
Project Summary - Center for Viral Systems Biology (CViSB) The COVID-19 pandemic is a stark reminder of the threat posed by infectious diseases, but other priority pathogens, such as Lassa and Ebola viruses, continue to pose significant chal…
Posted May 21, 2026
A smart cell drug (SmaCD) delivery platform for mobile, targetable, and self-regulated combination therapy: a model project to rescue antibodies from Alzheimer's disease (AD) clinical trial failures
US National Institute on Aging · grant
PROJECT SUMMARY / ABSTRACT As with many other diseases, Alzheimer’s disease (AD) is a multifactorial disorder consisting of multiple pathologies that are each known to be deleterious in their own right. Clinical trials assessing disease-mod…
Posted May 21, 2026
Support and Preparation for an Alzheimer's Research Career
US National Institute on Aging · grant
Alzheimer’s Disease and Related Dementias (ADRD) are the leading cause of dementia in those over the age of 65, leading to progressive memory loss and cognitive decline. Although the National Plan to address AD seeks to accelerate research …
Posted May 21, 2026
PTM-driven mechanisms of cell signaling
US National Institute of General Medical Sciences · grant
PROJECT SUMMARY This MIRA/R35 application is designed to replace our NIGMS R01 GM147310-01 and a recent NIGMS R01 application that was scored on first submission but rejected based on not being able to have two simultaneous NIGMS R01s. Foll…
Posted May 21, 2026
Effects of COVID-19 Related Medicaid Policy Changes in the Marshallese COFA Migrant Population
US NIH · grant
ABSTRACT Access to healthcare is a persistent public policy concern, particularly for Marshallese Compact of Free Association (COFA) migrants in the United States. This research addresses the impact of Medicaid policy changes, prompted by …
Posted May 21, 2026
Investigating the genetics and genomics of antiparasitic drug responses in a poultry model of ascariasis
US · IL National Institutes of Health (NIH) · grant
PROJECT SUMMARY Infections with the parasitic nematode Ascaris lumbricoides affect up to an estimated 1.2 billion people worldwide, causing significant disease and accounting for the loss of 749,000 Disability Adjusted Life Years (DALYs) a…
Posted May 21, 2026
Adolescent Girls’ Risk for Suicide Across the Menstrual Cycle: Examining Stress and Negative Valence Systems Longitudinally
US · IL National Institutes of Health (NIH) · NAICS 541715 · $1-5M · grant
Project Summary/Abstract Suicide is the second leading cause of death (behind accidents) among those ages 10-34 years in the US and is the cause of mortality most strongly linked to mental illness. Starting at approximately age 12 years, th…
Posted May 21, 2026
The Role of Annexin A1 Expression in Glioblastoma-Associated Astrocytes
US · MA · Boston NIH · NAICS 541714 · grant
Astrocytes profoundly influence immunity, but they are negligibly characterized in glioblastoma (GBM). My preliminary data suggest that GBM-associated astrocytes expressing annexin A1 (ANXA1) contribute to immunosuppression in GBM: 1) ANXA1…
Posted May 21, 2026
Skin cell heterogeneity in sensitivity to mustard-induced cell death
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
Abstract Sulfur mustard, also known as mustard gas, is a threat in chemical warfare and terrorism. Although major advances have been made in understanding mustard-induced skin injury, effective countermeasures are lacking. Under an R34 gran…
Posted May 21, 2026
Interdisciplinary Training Program in Skin Biology
US · CA · Irvine NIH · grant
Abstract We propose a new interdisciplinary skin biology training program at the University of California, Irvine. The Program builds on a strong group of skin biology mentors affiliated with a NIAMS-funded Skin Biology and Disease Research…
Posted May 21, 2026
Skin Biology Resource-Based Center at UCI
US · IL National Institutes of Health (NIH) · grant
The broad, long-term objective of the UC Irvine Skin Biology and Disease Resource-based Center is to promote significant and innovative discoveries in regulatory mechanisms in skin biology and disease through cross-fertilization between mu…
Posted May 21, 2026
Circadian Clock Regulation in Skin
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT The circadian clock, an ancient, evolutionary conserved timing system required for optimal function of organs and organismal lifespan, is active in peripheral tissues, including the skin. Clocks in peripheral organs…
Posted May 21, 2026
Transcriptional Co-Regulators in Epidermis
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT Although the epidermis is composed of morphologically distinct layers, single-cell RNA-seq experiments indicate that epidermal differentiation does not progress in discrete steps at a transcript level but is instead…
Posted May 21, 2026
Core D: Digital Pathology and CyTOF
US · MD Johns Hopkins University · grant
PROJECT SUMMARY The Digital Pathology and Mass Cytometry Core (Core D) will provide state-of-the-art technologies to enable high-parameter single-cell proteomic profiling for all the Research Projects in the proposed P01 Program Project Gra…
Posted May 21, 2026
Opportunities for Pathology Trainees in Cancer Research
US · MD NIH RePORTER · grant
Project Summary/Abstract Pathologists are uniquely positioned to contribute to cancer research. Their familiarity with disease classifications and pathogenesis, physical manifestations of tumors in tissue, and clinical challenges in cancer …
Posted May 21, 2026
Pathology Core
US National Institute on Alcohol Abuse and Alcoholism · grant
PROJECT SUMMARY The purpose of this shared resource is to provide human tissues, biological fluids, and expert pathologic interpretation for project investigators. The Pathology Core will work with an existing resource, the GI SPORE Tissue …
Posted May 21, 2026
Precision characterization of antimicrobial resistance gene dynamics in bloodstream infection risk after hematopoietic stem cell transplantation
US · NC NIH · grant
PROJECT SUMMARY Candidate: Tessa M. Andermann, MD, MPH is a fellowship-trained Infectious Diseases specialist who has been involved in patient-oriented research throughout her medical training. As an Assistant Professor of Medicine at UNC, …
Posted May 21, 2026
State-dependent modulation of retinothalamic axonal boutons
US National Eye Institute · grant
Summary Perception does not depend on environment alone, but also on brain state. Work from our lab and others show that visual responses to certain features are selectively gated depending on an animal's arousal state. What are the circuit…
Posted May 21, 2026
Roles of cortical neuromodulation and offline reactivation in memory consolidation of emotionally salient visual experiences
US National Institute of Mental Health · grant
Summary What are the mechanisms by which we selectively remember sensory cues associated with salient outcomes? Salient sensory experiences activate distributed patterns of neurons in regions including sensory cortex, amygdala, and hippocam…
Posted May 21, 2026
High-dimensional chemical targeting of multiple neuron types to regulate energy balance
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
Summary Recent drugs for treating obesity and diabetes, while promising, have major side effects. For example, drugs that reduce food intake by targeting the melanocortin-4 receptor (MC4R) or the glucagon-like peptide-1 receptor (GLP1R) ind…
Posted May 21, 2026
Multiplexed Sensing and Control of Neuromodulators and Peptides in the Awake Brain
US National Eye Institute · grant
Summary Imbalanced levels of neuromodulators and other chemical signals contribute to a host of neurological disorders. Yet, previous studies describing these effects often examine only one molecule at a time, and typically provide a static…
Posted May 21, 2026
ASU Roybal Administrative Core
US National Institute on Aging · grant
Abstract (The Administrative Core) Living alone has become increasingly common over the past few decades among older adults, including those with cognitive decline (defined as subjective cognitive decline [SCD], mild cognitive decline [MCI]…
Posted May 21, 2026
Promoting a reparative instead of a degenerative outcome from loading of fatigue-damaged tendons
US · IL NIH RePORTER · grant
Tendinopathies are common injuries that typically result from accumulation of sub-rupture fatigue damage. We have developed an in vivo model of sub-rupture fatigue damage accumulation using the rat patellar tendon to investigate the onset a…
Posted May 21, 2026