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20,086 contracts

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Showing 25 / 20086 · page 49/804
Addressing Food Access and Physcial Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT Diabetes is one of the most pressing public health challenges in the U.S., with over 98 million adults – more than one in three – already living with pre-diabetes mellitus (pre-DM), placing them at heightened risk f…
Posted May 21, 2026
Decoding ensemble dynamics from cortico-amygdalar circuits during social choice
US National Institute of Mental Health · grant
Project Summary Social relationships are a key component of human health and survival and impairments in social behavior have a major impact in many psychiatric conditions. Yet despite the importance of social context to health, there remai…
Posted May 21, 2026
CTSA K12 Program at Wake Forest
US National Center for Advancing Translational Sciences · grant
The Wake Forest (WF) Clinical and Translational Science Institute (CTSI) joined the CTSA consortium in 2015 with the goal of catalyzing our health system’s transformation into an exemplary Learning Health System (LHS). Since then, we have e…
Posted May 21, 2026
Pilot & Feasibility Program
US · NC NORTH CAROLINA DIABETES RESEARCH CENTER (NCDRC) · $25k-100k · grant
NORTH CAROLINA DIABETES RESEARCH CENTER (NCDRC): PILOT AND FEASIBILITY CORE SUMMARY To provide research support to explore feasibility of concepts related to the NCDRC’s goals and provide a mechanism to generate sufficient preliminary data …
Posted May 21, 2026
Integrated Reward-Inflammation Model of First Onset of Major Depression in Adolescence
US National Institute of Mental Health · grant
7. Project Summary/Abstract Adolescence is an “age of risk” for the emergence of 1st onset of major depressive disorder (MD). Despite its prevalence and public health significance, major unanswered questions exist regarding the mechanisms i…
Posted May 21, 2026
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in Adolescence
US · IL NIH · grant
7. Project Summary/Abstract Adolescence is an “age of risk” for the emergence of first onset of bipolar spectrum disorders (BSD). Despite their prevalence and public health significance, major unanswered questions exist regarding the mechan…
Posted May 21, 2026
Data Management and Statistics Core
US National Institute on Aging · grant
Data Management and Statistics Core Summary The Data Management and Statistics Core (DMSC) will foster the Yale ADRC through rigorous collaborative engagement with investigators, the training of scientists, and the development of novel stat…
Posted May 21, 2026
Design Statistics Core (D)
US · IL National Institute on Aging (NIA), NIH · grant
The design and analysis of embedded pragmatic clinical trials (ePCTs), particularly those evaluating the effectiveness of interventions to improve dementia care, pose unique challenges requiring specialized expertise. As such, the Design an…
Posted May 21, 2026
Antigen presentation during Trypanosoma cruzi infection: in search of a new effective vaccine
US National Institute of Allergy and Infectious Diseases · grant
PROJECT SUMMARY/ABSTRACT Chagas disease, caused by the parasite Trypanosoma cruzi, is a significant global health concern, primarily affecting Latin America but also impacting regions in Europe and the US. Currently, there are limited treat…
Posted May 21, 2026
Immune System Development and Regulation
US National Institute of Allergy and Infectious Diseases · grant
This program requests the continuation of 4 predoctoral positions for training in immune system development and regulation (ISDR). The program includes 26 faculty trainers with expertise in the development and regulation of the immune syste…
Posted May 21, 2026
Purinergic Receptors in Myeloma
US · IL NIH · grant
Project summary The purpose of this project is to identify novel regulators of ER homeostasis in malignant plasma cells that can be targeted to induce the death of these cells and/or prevent upstream events that foster plasma cell malignanc…
Posted May 21, 2026
Biochemical Mechanisms for Sustained Humoral Immunity
US · IL NIH · grant
Project summary Antibody-secreting plasma cells play critical roles in health and disease, yet little is known about the biochemical mechanisms controlling antibody synthesis and secretion or how these pathways intersect with pathways contr…
Posted May 21, 2026
Proteasome Targeting for Alloreactive Plasma Cells
US · IL NIH · grant
Abstract The induction of plasma cells that secrete antibodies against donor tissue alloantigens is a major barrier to successful transplantation. Moreover, because many plasma cells are remarkably long-lived, the resulting antibody titers …
Posted May 21, 2026
Language is Medicine: A Caregiver-Implemented Language Intervention to Prevent Developmental Delay in Dine Toddlers
US National Institute on Minority Health and Health Disparities · grant
PROJECT SUMMARY/ABSTRACT Native American (NA) toddlers and preschoolers experience a high rate of preventable developmental delay (DD) which contributes to decreased kindergarten readiness and often results in the need for special education…
Posted May 21, 2026
UCSD Integrated Cardiovascular Epidemiology Fellowship
US National Heart Lung and Blood Institute · grant
SUMMARY/ABSTRACT The objective of the T32 funded “Integrated Fellowship on the Epidemiology and Prevention of Cardiovascular Disease" is to rigorously train physicians and behavioral scientists in epidemiologic and behavioral research meth…
Posted May 21, 2026
Optimized Strategies to Support Implementation of Remote Patient Monitoring for Diabetes Management in High-Risk Pregnancy: A Feasibility Study
US National Institute of General Medical Sciences · grant
RESEARCH PROJECT 2: PROJECT SUMMARY/ABSTRACT Women residing in rural areas of the United States (U.S.) face higher maternal health risks, including a 9% increased likelihood of severe maternal morbidity and mortality compared to their urb…
Posted May 21, 2026
Colorado Nurse Family Heart Trial for the ENRICH program
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Cardiovascular disease (CVD) is the leading cause of death in the United States, with disparately greater impact on racial/ethnic minorities and lower-income individuals. Risk for CVD begins very early in life as adverse exp…
Posted May 21, 2026
Auditory-perceptual motor speech features in preschoolers: Norms and utility in differentiating childhood apraxia of speech and dysarthria
US · IL NIH · grant
PROJECT SUMMARY Childhood apraxia of speech (CAS) and dysarthria are two neurological motor speech disorders that can have long-term negative effects on communication and participation for 1-2/1000 children in the general population and up …
Posted May 21, 2026
04 Immunology
US · IL National Cancer Institute (NCI) · $5M-25M · grant
PROJECT SUMMARY/ABSTRACT The Immunology Program includes 30 members (26 primary, 3 associate, 1 adjunct) from 9 departments. The program is led by Dr. James Allison, an international authority on exploring fundamental mechanisms of the immu…
Posted May 21, 2026
Comparative Data Analytics Core
US National Institute on Aging · grant
Project Summary (Comparative Data Analytics Core) Researching aging biology presents unique methodological challenges. To maximize the impact of aging research, it is essential to have a wide range of statistical expertise within and suppor…
Posted May 21, 2026
Stargardt/ABCA4 disease in African Americans
US · IL NIH · grant
Project summary/Abstract Disease-associated variation in the ABCA4 gene has emerged as the most prevalent cause of Mendelian retinal disease affecting an estimated 50,000 people in the United States. The extensive clinical heterogeneity of …
Posted May 21, 2026
Development of a Novel Therapeutic for Melioidosis
US · IL NIH · grant
To support the advanced development of candidate therapeutics for biodefense pathogens or emerging infectious diseases. The supported research and development activities will progress the therapeutic product development and may include lead…
Posted May 21, 2026
Research Project 1 - Allerton
US · IL NIH · grant
Project Summary Heart failure with preserved ejection fraction (HFpEF) will soon become the predominant form of heart failure. Patients with cardiometabolic HFpEF have multiple co-morbidities including obesity, hypertension, and diabetes. T…
Posted May 21, 2026
Viral Testing Core
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT – VIRAL TESTING CORE Continuous, accurate surveillance for agents of concern is an essential requirement for maintenance of a specific pathogen-free (SPF) breeding colony. In 2009, we transitioned from testing at of…
Posted May 21, 2026
Exercise for Memory Rehabilitation in Epilepsy
US · IL NIH · grant
Project Summary/Abstract Approximately 50% of the 3.4 million persons with epilepsy (PWE) in the U.S. have cognitive problems with memory deficits reported most commonly. Memory deficits negatively contribute to the personal and profession…
Posted May 21, 2026