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Showing 25 / 20086 · page 50/804
Veterinary Medicine Research Branch
US · IL National Institute of Mental Health (NIMH), National Institutes of Health (NIH) · grant
The NIMH Veterinary Medicine Research Branch (VMRB) has successfully provided veterinary medical, husbandry and research support to over twenty-four (24) principal investigators in the NIMH IRP, with over forty-seven (47) active animal stud…
Posted May 21, 2026
Veterinary Research and Resources Section
US National Eye Institute · grant
The NEI Veterinary Research and Resources Section (VRRS) has successfully provided support to veterinary medical, husbandry and research support to the NEI ACUC and approximately twenty-two (22) principal investigators in the NEI DIR with s…
Posted May 21, 2026
Posttranslational regulation of macropinocytosis in pancreatic cancer
US · IL NIH · grant
The majority of pancreatic ductal adenocarcinoma (PDAC) patients present with late-stage, metastatic disease that is often resistant to therapeutics, resulting in the lowest survival rate of all major cancers. Metabolic rewiring in response…
Posted May 21, 2026
Interactive Outbreak Simulator: A Robust and Customizable Platform for Socio-Epidemiological Insights
US · IL NIH · grant
Project Summary / Abstract The long-term objectives of this work are to develop a platform for modeling disease transmission during outbreaks, and to deploy that platform into research laboratories and public health settings across the Unit…
Posted May 21, 2026
Impact of Developmental Glutamatergic Signaling on Oligodendrocyte Differentiation
US National Institute of Neurological Disorders and Stroke · grant
Project Oligodendrocytes nervous propagation. involves proliferation development. developing chemogenetically preliminary precursor development of also maturation. early Here elucidate glutamate Summary (OLs) produce myelin, a lipid rich me…
Posted May 21, 2026
Large-scale Implementation of Community Co-led Maternal Sepsis Care Practices to Reduce Morbidity and Mortality from Maternal Infection
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
In the United States, infection is now the most common cause of direct maternal mortality and the third leading cause overall after cardiovascular conditions and other pre-existing medical conditions. Nationally, there has been no improveme…
Posted May 21, 2026
Iron Based Coupling Media (IBCM) for MRI-guided Transcranial Ultrasound Surgeries
US National Institute of Biomedical Imaging and Bioengineering · grant
Project Summary/Abstract Fatal or impairing neurological diseases, including movement disorders, brain cancers, psychological disorders, epilepsies, malformations, and memory disorders, impose heavy burdens on both individuals and society a…
Posted May 21, 2026
Mixed methods research to increase engagement and smoking abstinence among African Americans enrolled in Quitline text messaging services
US National Institute on Drug Abuse · grant
Cigarettes are used by over 34 million U.S. adults and cause more than 480,000 deaths annually due to smoking and smoke exposure. Despite smoking at similar rates and consuming less cigarettes per day, African Americans are more likely to d…
Posted May 21, 2026
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
Project Summary/Abstract Postpartum smoking relapse rates have remained stagnant for over a decade with more than 50% of those who are able to achieve smoking abstinence during pregnancy relapsing within the first few months after childbirt…
Posted May 21, 2026
Research Project 3
US National Institute on Drug Abuse · grant
PROJECT SUMMARY American Indians (AIs) have the highest rate of prescription opioid misuse of any sociodemographic group in the United States (US). Increasing rates of opioid misuse have led to increased prevalence of injection drug use (I…
Posted May 21, 2026
Adapting a Network-Oriented HIV Prevention Intervention for Rural People Who Inject Drugs (PWID)
US National Institute on Drug Abuse · grant
Project Summary Recent HIV outbreaks among rural people who inject drugs (PWID) highlighted significant gaps in HIV prevention science. HIV risk behaviors among PWID are influenced by several factors, including access to sterile injection e…
Posted May 21, 2026
Examining the Role of a Pathogenic HTT Isoform, HTT1a, in Somatic Expansion and RNA Aggregation in Huntington's Disease
US National Institute of Neurological Disorders and Stroke · grant
PROJECT SUMMARY Huntington’s Disease (HD) is caused by expanded CAG repeats in exon 1 of the Huntingtin (HTT) gene, resulting in transcription of mutant HTT mRNA and translation of mutant protein, both of which form nuclear aggregates in ne…
Posted May 21, 2026
A multispecies system for elucidating proliferative control mechanisms during mammalian skin and musculoskeletal regeneration
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
Abstract While antifibrotic therapies continue to advance, they fall short when treating large or chronic wounds. Essential to developing new regenerative strategies is a comprehensive understanding of how cell proliferation is activated, …
Posted May 21, 2026
MARC at the University of Colorado Denver
US National Institute of General Medical Sciences · grant
PROJECT SUMMARY The diversity of the United States population is not reflected in its biomedical sciences workforce, with the greatest disparities at the highest levels of degree attainment and in careers that require advanced degrees. Inst…
Posted May 21, 2026
Investigating the in vivo regulation of Dynein activity
US National Institute of General Medical Sciences · grant
The establishment and maintenance of polarity is a fundamental feature of eukaryotic cells. Molecular motors within cells transport a variety of cargo including RNAs, proteins, vesicles, and organelles. The asymmetric distribution of these …
Posted May 21, 2026
Biomarker validation for intraductal papillary mucinous neoplasms of the pancreas
US National Cancer Institute · grant
PROJECT SUMMARY/ABSTRACT: Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are cystic tumors that represent a radiographically identifiable precursor lesion of pancreatic cancer. Currently, IPMN represent our best opportunity…
Posted May 21, 2026
Orientia tsutsugamsuhi promotes interplay between circadian rhythm and hypoxic responses
US National Institute of Allergy and Infectious Diseases · grant
SUMMARY Converting the host cell into a supportive niche is essential for intracellular pathogen survival and replication. Orientia tsutsugamushi is a genetically intractable obligate intracellular bacterium that causes scrub typhus, a glob…
Posted May 21, 2026
Multifunctional roles of an Orientia tsutsugamushi nucleomodulin
US National Institute of Allergy and Infectious Diseases · grant
SUMMARY Orientia tsutsugamushi is a genetically intractable obligate intracellular bacterium that causes scrub typhus, a globally emerging infection with a high fatality rate. Disease progression depends on bacterial-driven modulation of ho…
Posted May 21, 2026
MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA) - FIELD CENTER
US National Heart Lung and Blood Institute · grant
The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the correlates, predictors, and progression of subclinical cardiovascular disease (CVD) in a diverse population-based sample of men and women aged 45-84 who had no evidence of c…
Posted May 21, 2026
Cardiovascular Health Trajectories from Birth Thru Adolescence in A Diverse Cohort of Children
US National Heart Lung and Blood Institute · grant
Abstract The overarching goal of this proposal is to identify CVH trajectories from birth through age 20 among a diverse cohort of 7,000 children and their families who already have clinical phenotyping to which we will add detailed behavio…
Posted May 21, 2026
Determining the role of astrocyte BMP signaling in cortical astrocyte heterogeneity
US National Institute of Neurological Disorders and Stroke · grant
PROJECT SUMMARY Astrocytes, like neurons, display regional and intra-regional heterogeneity in both function and transcriptional state. This heterogeneity impacts neighboring neurons, making it imperative to identify on a molecular level wh…
Posted May 21, 2026
Targeted Degradation of Extracellular Proteins to Enhance Brain Plasticity
US National Institute of Neurological Disorders and Stroke · grant
PROJECT SUMMARY The young brain displays remarkable plasticity. This includes an ability to remodel neuronal synaptic connections to learn new tasks in health, as well as being able to repair connections and restore function after injury. I…
Posted May 21, 2026
Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide
US National Institute of Mental Health · grant
ABSTRACT Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Although promising approaches are available for preventative interventions with youth at-risk for suicide, …
Posted May 21, 2026
Building a Contextually Triggered Just-in-Time Intervention for Opioid UseDisorder: Stakeholder Evaluation and User Centered Design
US National Institute on Drug Abuse · grant
Abstract The opioid epidemic represents a major public health crisis in the U.S. Although medications such as buprenorphine are the current gold standard treatment for individuals diagnosed with opioid use disorder (OUD), a significant prop…
Posted May 21, 2026
BRITE 2.0: A just-in-time adaptive intervention for suicide safety planning in adolescents
US National Institute of Mental Health · grant
ABSTRACT Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. While suicide safety planning interventions can be effective in reducing suicidal behavior, adolescents oft…
Posted May 21, 2026