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Showing 25 / 20086 · page 51/804
Role of stromal inflammatory signaling in the aging of lung resident lymphocytes
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Immune system dysfunction has been implicated in the pathogenesis of several age-related lung diseases. Interestingly, multiple recent studies have identified the tissue microenvironment as playing a critical role in the pat…
Posted May 21, 2026
Share plus: Continuous Glucose Monitoring with Data Sharing in Older Adults with T1D and Their Care Partners
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
Older adults with type 1 diabetes (T1D) have an increased risk of hypoglycemia and hyperglycemia that can result in grave health consequences, such as seizures, falls, and myocardial infarctions. Care partners (e.g., spouses, friends) regul…
Posted May 21, 2026
Minnesota Advancing Science and Cancer EducatioN Discoveries (MASCEND)
US National Cancer Institute · grant
This renewal of our M-ASCEND Program to the NCI Youth Enjoy Science (YES) mechanism leverages 17 years of cancer research-focused mentored education activities at the University of Minnesota (UMN) Masonic Cancer Center and PHDR Program in t…
Posted May 21, 2026
Cancer Related Health Disparities Training Program
US National Cancer Institute · grant
PROJECT ABSTRACT/SUMMARY This is a proposal for the competing continuation of the University of Minnesota T32 Cancer Health Disparities Training Program, funded by NCI since 2011. Disparities in cancer incidence, prevalence, screening, trea…
Posted May 21, 2026
Center for Chronic Disease Reduction and Equity Promotion Across Minnesota (C2DREAM)
US National Institute on Minority Health and Health Disparities · grant
Posted May 21, 2026
Clinical and Translational Science Workforce Development through a Statewide Community College Partnership
US National Center for Advancing Translational Sciences · grant
This R25 Research Education Module, leveraging the infrastructure of the Indiana Clinical and Translational Sciences Institute (I-CTSI), will foster development of the clinical and translational workforce within Indiana through education an…
Posted May 21, 2026
Histology and Histomorphometry Core (HHC)
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
PROJECT SUMMARY/ABSTRACT The Histology and Histomorphometry Core (HHC), Core B, will provide inhouse expertise, techniques, equipment, and technical innovation to facilitate ICMH investigators from vastly different subspecialties to use his…
Posted May 21, 2026
Enabling systemic delivery of europium-containing contrast agents for magnetic resonance imaging
US National Institute of Biomedical Imaging and Bioengineering · grant
The ability to image the presence or absence of oxygen is of paramount importance to the study of biochemistry, medicine, and multiple diseases. Hypoxia is linked to a variety of diseases including kidney disease; hepatic and neurological t…
Posted May 21, 2026
Omics Core
US · IL NIH · grant
SUMMARY The Omics core (Core 2) will support the overall U19 proposal by generating multiple layers of omics data from biospecimens collected as part of the well characterized cohorts of ADNI, MCSA and 5 ADRCs (Mayo Clinic, Indiana Universi…
Posted May 21, 2026
CE24-012 - The Impact of Recreational Cannabis Legalization on Substance Use Outcomes
US National Center for Injury Prevention and Control · grant
PROJECT ABSTRACT This project will rigorously assess the impact of recreational cannabis legalization on opioid use and overdoses across the United States. With nearly half of the U.S. population living in states where recreational cannabis…
Posted May 21, 2026
Treatment of Knee Osteoarthritis via Intra-articular Delivery of an Immunosuppressive Enzyme
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
Project Summary In osteoarthritis (OA), intra-articular inflammation is a key mediator of joint destruction and chronic joint pain. Unfortunately, current strategies to control joint inflammation have largely failed. To address this challe…
Posted May 21, 2026
Innervation of the knee and TMJ
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
The over-arching goal for the RE-JOIN Consortium is to define how the neurons that mediate chronic joint pain innervate different articular and peri-articular tissues, with a focus on the knee and temporomandibular joint (TMJ). With an impr…
Posted May 21, 2026
STepped Exercise Program for Knee Osteoarthritis: The STEP-KOA Study
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
Knee osteoarthritis (OA) is a leading cause of pain and disability. Exercise is a first-line component of care for knee OA. However, the majority of individuals with knee OA are inactive, and exercise-based physical therapy (PT) is underuti…
Posted May 21, 2026
HSR&D Research Career Scientist Award
US Veterans Affairs · grant
This proposed Research Career Scientist award is to support the activities of Dr. Kelli Allen, an established Department of Veterans Affairs (VA) Health Services Research and Development (HSR&D) investigator, allowing her to her expand her …
Posted May 21, 2026
Precision Medicine Approach to Exercise-Based Interventions for Veterans with Knee Osteoarthritis
US Veterans Affairs · grant
Background: Knee osteoarthritis (OA) is a leading cause of pain and disability, and Veterans have markedly greater rates than non-Veterans. Exercise is a core component of care for knee OA, associated with modest average improvements in pai…
Posted May 21, 2026
Boosting Exercise Adherence in Knee Osteoarthritis (BOOST-OA)
US Veterans Affairs · grant
Background: Knee osteoarthritis (OA) is a leading cause of functional limitations among Veterans. Physical therapy (PT), with a focus on exercise, has strong evidence for improving physical function and other outcomes among individuals with…
Posted May 21, 2026
Structure and function of the monotopic phosphoglycosyl transferase superfamily: Initiators of biosynthesis of complex bacterial glycoconjugates
US National Institute of General Medical Sciences · grant
Complex glycoconjugates play a pivotal role in bacterial survival, colonization, and virulence, and contribute to the interactions between symbiotic and pathogenic bacteria and their human hosts. Assembly of these macromolecules is initiate…
Posted May 21, 2026
Social Relationship Qualities as Predictors of Health & Aging from Adolescence through Mid-Adulthood
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
Project Summary Public health efforts in adolescence aimed at life course physical health promotion have to date focused almost exclusively on addressing physiological risk factors and health behaviors (e.g., weight, smoking, etc.). This pr…
Posted May 21, 2026
Drug Screening Platform in the Light-Responsive Human Eye
US · IL NIH · small business · grant
Blinding diseases rob independence from millions of people in aging societies with poor metabolic and cardiovascular health. There are currently almost 1,000 planned or active clinical trials for investigational new drugs (INDs) to address …
Posted May 21, 2026
Contribution of CdiA to Pseudomonas aeruginosa pathobiology
US National Institute of Allergy and Infectious Diseases · grant
Project Summary/Abstract Pseudomonas aeruginosa is a leading cause of healthcare-acquired infections worldwide. Many globally- distributed high-risk strains are emerging due to an increase in antibiotic resistance and acquisition of novel v…
Posted May 21, 2026
Discovery of GPR52 ligand probes for cocaine use disorder
US National Institute on Drug Abuse · grant
PROJECT SUMMARY Abuse of psychostimulants represents a major public health problem in the United States. Continued misuse of stimulants escalates in vulnerable individuals to a substance use disorder (SUD). SUDs are debilitating conditions …
Posted May 21, 2026
Altered Central Multisensory Processing in Post-concussion Vestibular Dysfunction
US National Institute of Neurological Disorders and Stroke · grant
Project Summary/Abstract Patients with persistent post-concussion vestibular dysfunction (PCVD) demonstrate visual motion sensitivity characterized by visual and motion stimuli inducing vestibular symptoms. We hypothesize that patients may…
Posted May 21, 2026
PRIME HRrEF: Novel Exercise for Older Patients with Heart Failure with Reduced Ejection Fraction
US National Institute on Aging · grant
Abstract. Heart failure (HF) is the leading cause of hospitalization among Americans ≥65 years old with 5.7 million sufferers and an annual of ~$39.2 billion. Patients with HF suffer from shortness of breath, fatigue and exercise intoleran…
Posted May 21, 2026
Explaining the potential role of physical activity in employment disparities after breast cancer
US National Institute on Minority Health and Health Disparities · grant
PROJECT SUMMARY Breast cancer is the most diagnosed cancer in the world with the largest survivorship group. The rise of breast cancer survivors (BCS) living longer, healthier lives merits attention to important areas of cancer survivorship…
Posted May 21, 2026
Role of epithelial ROS signaling in mediating psychological stress-induced mucosal dysfunction and colitis predisposition
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
PROJECT SUMMARY/ABSTRACT: Inflammatory bowel diseases (IBD) are becoming more prevalent in the US and represent a major societal health concern. Exposure to psychosocial stressors increases the likelihood of developing IBD in genetically pr…
Posted May 21, 2026