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20,086 contracts

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Showing 25 / 20086 · page 134/804
Utah Center for Promotion of Work and Employment Research (U-POWER)
US National Institute for Occupational Safety and Health · grant
ABSTRACT (OVERALL CENTER) The Utah Center for Promotion of Work Equity Research (U-POWER) envisions work and workplaces that are safe, healthy, and equitable. Together, we can ensure that the conditions of work promote the health and well- …
Posted May 21, 2026
Exploratory studies of cellular resistance to MTA-cooperative PRMT5 inhibitors in MTAP-loss tumors.
US National Cancer Institute · grant
PROJECT SUMMARY/ABSTRACT MTAP is deleted in approximately 15% of all human malignancies and co-occurs in 80-90% of all CDKN2A- /CDKN2B-deleted cancers, including but not limited to cancers of the lung, gastric system, brain, breast, urinary…
Posted May 21, 2026
Genetically Engineered Mouse Models (GEMM)
US National Cancer Institute · grant
PROJECT SUMMARY/ABSTRACT – GENETICALLY ENGINEERED MOUSE MODELS SHARED RESOURCE The Genetically Engineered Mouse Models Shared Resource (GEMMSR), formerly the Transgenic Gene Knockout Shared Resource, provides St. Jude Comprehensive Cancer C…
Posted May 21, 2026
Translation Core
US National Institute of Environmental Health Sciences · grant
TRANSLATIONAL CORE - ABSTRACT The Translational Core (TC) will be the primary focus of the Center and support scientists, community members, and healthcare providers in generating and disseminating critical research findings in children's e…
Posted May 21, 2026
Predoctoral Training Program in Signaling and Cellular Regulation
US National Institute of General Medical Sciences · grant
Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Program Summary The goal of this training grant proposal is to prepare predoctoral trainees for productive …
Posted May 21, 2026
Select Series Cyclic IMS Mass Spectrometry System
US NIH Office of the Director · grant
PROJECT SUMMARY We request funds to purchase a high-resolution and high-sensitivity liquid chromatography-mass spectrometry system for the analysis of small molecules and biomolecules at the University of Colorado Boulder (CU-Boulder) as we…
Posted May 21, 2026
Molecular and Cellular Dynamics in Mammalian Signal Transduction
US National Institute of General Medical Sciences · grant
PROJECT SUMMARY This MIRA proposal addresses two important avenues of discovery made by our laboratory. In Project 1, we will examine a novel mechanism for allosteric regulation of the MAP kinase, ERK2. This project advances the protein kin…
Posted May 21, 2026
Asian American Community Cohort of the New York Metropolitan Area
US National Heart Lung and Blood Institute · grant
ABSTRACT Asian Americans (AsA) are the fastest growing racial/ethnic group in the US, projected to double to 43 million people by 2050; however, our understanding of the factors that lead to disease or health in AsA is limited because AsA o…
Posted May 21, 2026
Coronary Atherosclerotic Burden in AsA-NHPI: the Role of the Gut Microbiome
US National Heart Lung and Blood Institute · grant
Cardiovascular disease (CVD) is the leading cause of death among Asian American, Native Hawaiian, and Pacific Islander (AsA-NHPI) adults, with rates varying across subgroups. However, the distribution of CVD risk factors in AsA-NHPI populat…
Posted May 21, 2026
Epidemiology & Cancer Control (ECC) Research Program
US National Cancer Institute · grant
PROJECT SUMMARY/ABSTRACT The vision of the Epidemiology and Cancer Control Program (ECC) is to reduce the cancer burden in the PCC catchment area and beyond. To achieve this vision, we conduct innovative and high impact research, discove…
Posted May 21, 2026
Maintenance and Enhancement of the Asian American enriched Cohort
US National Institute of Environmental Health Sciences · grant
Over 90% of Asian American (AsA) adults are either first-generation (foreign-born) or second-generation immigrants, experiencing a substantial environmental and sociocultural transition in this country. Yet, most environmental epidemiology …
Posted May 21, 2026
Vascular contribution to white matter lesions and motor dysfunction in AD and ADRD
US National Institute on Aging · grant
Most Alzheimer’s Disease (AD) patients experience severe motor impairment at the later stage of disease and 10 - 40% of AD patients exhibit signs of motor dysfunction at even earlier stages of AD. Furthermore, changes in motor function ofte…
Posted May 21, 2026
Combination Therapy of Home-based Trans-cranial Direct Current Stimulation and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms in Older Adults with Knee Osteoarthritis
US National Institute of Nursing Research · grant
ABSTRACT The long-term goal of this project is to improve clinical pain and symptoms for older adults with knee osteoarthritis (OA) using home-based nonpharmacological approaches. Knee OA is one of the most common pain conditions among peop…
Posted May 21, 2026
Engineered biomimetic collective cancer invasion models for screening chemotherapeutic agents
US National Cancer Institute · grant
PROJECT SUMMARY Metastasis is the primary cause of cancer mortality, yet few breast cancer drugs effectively inhibit metastasis. Breast cancer cells use collective migration to remodel and align surrounding extracellular matrix (ECM) fibril…
Posted May 21, 2026
Genetic and molecular basis of hematopoietic abnormalities in ZTTK syndrome
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Individuals with rare genetic diseases do not receive attention from the medical and research community. One out of two patients diagnosed with a rare disease is a child, meaning that patients and their families must endure …
Posted May 21, 2026
Host immunity in the lung is determined by the enhanced utilization of glucose by multi-drug resistant Klebsiella pneumoniae
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY/ABSTRACT When the airways of children dependent on ventilators become infected with multi-drug resistant (MDR) organisms, such as Klebsiella pneumoniae (KP), their risk of acute deterioration and even death increases. Diffic…
Posted May 21, 2026
Core C: Data Analytics Core
US National Cancer Institute · grant
Project Summary The Data Analytics Core (Core C) brings together a team of experienced professionals to assist with biostatistics and bioinformatics methodologies as well as data management for the UT Southwestern Medical Center (UTSW) Kidn…
Posted May 21, 2026
Core C - Data Science
US National Cancer Institute · grant
The Data Science Core (Core C) will offer comprehensive biostatistical and bioinformatic support to the UT Southwestern (UTSW) Liver Cancer SPORE. Core C, co-directed by Drs. Chul Ahn and Tao Wang, consists of expert members integrated into…
Posted May 21, 2026
Biostatistics Shared Resource
US National Cancer Institute · grant
The Biostatistics Shared Resource (BSR) is a centralized resource that provides state-of-the-art biostatistical support for investigators conducting cancer research at Simmons Comprehensive Cancer Center (SCCC). Advances in biotechnologies …
Posted May 21, 2026
Synergistic Effects of Unacylated Ghrelin and Endurance Exercise on Sarcopenia and Mobility Loss
US National Institute on Aging · grant
Project Summary/Abstract Sarcopenia, the progressive loss of muscle mass and function, universally impacts the aging population, contributing to loss of mobility and independence in older adults. With the rapid growth of the aging populatio…
Posted May 21, 2026
Project 1: Syncing Screening and Services for Suicide Prevention across Health and Justice Systems
US National Institute of Mental Health · grant
PROJECT SUMMARY As suicide rates in the United States continue to rise, with nearly 50,000 suicide deaths and over 1 million suicide attempts annually per most recent data, increased attention has been paid to how to best integrate and coor…
Posted May 21, 2026
Embedded Mental Health Services Postdoctoral Research Training in Health Systems
US National Institute of Mental Health · grant
PROJECT SUMMARY This application establishes a new T32 training program in embedded mental health services research in health systems leveraging the resources of the NIMH-funded Mental Health Research Network (MHRN). MHRN is a consortium of…
Posted May 21, 2026
Quality Measures to Advance Suicide Prevention and Care Across Health Systems
US National Institute of Mental Health · grant
PROJECT SUMMARY / ABSTRACT Suicide accounted for >48,000 deaths in the United States (US) in 2021. The annual rate has increased by >34% in the last 20 years. Suicide prevention is a top NIMH research priority. Evidence suggests that suicid…
Posted May 21, 2026
The Genomic Basis and Molecular Mechanisms of Speciation
US National Institute of General Medical Sciences · grant
PROJECT SUMMARY One of the fundamental problems in evolutionary biology is to understand the molecular genetic basis of speciation. Recent advances in speciation research have improved our understanding of interspecific divergence, but we s…
Posted May 21, 2026
Molecular Determinants of Pigmentation (MDoP)
US National Institute of Arthritis and Musculoskeletal and Skin Diseases · grant
“Molecular Determinants of Pigmentation (mDoP)” study aims to identify and characterize new genes and proteins essential for pigmentation development, melanosomes transportation, function and maintenance in humans. Pigmentation disorders (o…
Posted May 21, 2026