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Showing 25 / 20086 · page 58/804
NHLBI Training Program in Pharmacoepidemiology
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY / ABSTRACT Pharmacoepidemiology is a bridge science that uses tools from pharmacology, epidemiology and clinical medicine to understand the use, safety and effectiveness of drugs in large populations. The need for experts in…
Posted May 21, 2026
Core 08: Cyberinfrastructure Enhancement Core
US National Institute of General Medical Sciences · grant
The vision for the Cyberinfrastructure Enhancement (CE) Core is to strengthen the partner network, scale clinical accomplishments made in overcoming research related challenges during the previous cycle and create a sustainable growth model…
Posted May 21, 2026
U-RISE at the UNC Pembroke
US National Institute of General Medical Sciences · grant
The U-RISE program at the University of North Carolina at Pembroke aims to increase the number of students who pursue a terminal degree in biomedical or behavioral science and ultimately enter the biomedical research workforce. In order to …
Posted May 21, 2026
Indigenous Strengths as Solutions in a Public Health Crisis (Project ISH)
US National Institute on Drug Abuse · grant
ABSTRACT The Northwest Indian College (NWIC) in partnership with the Northwest Washington Indian Health Board (NWWIHB), proposes a Phase I application in response to the OTA-23-007 HEAL Initiative: Native Collective Research Effort to Enhan…
Posted May 21, 2026
Pilot Project Core
US National Institute on Minority Health and Health Disparities · grant
Project Summary/Abstract The primary goal of this P20 planning grant is to establish the Mni Sota Center for Climate Change and Health by developing a network of scientists and community members to build capacity for climate and health rese…
Posted May 21, 2026
Bioanalytical, Cardiometabolic Phenotyping, Imaging and Histology Core
US National Institute of General Medical Sciences · grant
CORE B – BIOANALYTICAL, CARDIOMETABOLIC PHENOTYPING, IMAGING AND HISTOLOGY CORE PROJECT SUMMARY/ABSTRACT The Cardiorenal and Metabolic Diseases Research Center (CMDRC) was established to enhance research infrastructure and provide mentoring…
Posted May 21, 2026
Retrosplenial Cortex Circuit Interactions Supporting Spatial Cognition and Memory
US National Institute of Neurological Disorders and Stroke · grant
This project proposes to investigate neurophysiological circuit mechanisms supporting spatial cognition and episodic memory. The retrosplenial cortex (RSC) is critical in these cognitive processes as RSC dysfunction is associated with spati…
Posted May 21, 2026
Motion Robust Relaxometry for Infant Neuroimaging
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
ABSTRACT: Quantitative relaxometry is a promising method for quantifying brain changes with early development and brain tissue differences as a function of genetics, environment or pathology. Relaxometry may be useful for assessing abnormal…
Posted May 21, 2026
Brain Imaging Core
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
Waisman Center investigators study intellectual and developmental disabilities (IDD) through investigating the brain structure and function in both animal models and individuals exhibiting or at risk for these conditions. The Waisman Brain …
Posted May 21, 2026
Getting Excited about Cortical Malformations: Discovering the Mechanisms Leading to Seizure-prone Neurons in Malformations of Cortical Development
US National Institute of Neurological Disorders and Stroke · grant
Abstract Background: Following surgical resection for intractable epilepsy caused by malformations of cortical development (MCDs), over 30% of children continue to have life-changing seizures. Mutations in genes of the mechanistic target o…
Posted May 21, 2026
HealthyCells: A Culturally-Tailored Smoking Cessation Smartphone Intervention for African Americans with Adjunctive Treatment for Sedentary Behavior
US National Institute on Minority Health and Health Disparities · grant
PROJECT ABSTRACT Successfully increasing cessation rates among African Americans would reduce the racial disparity in mortality between African Americans and Whites by up to 20%. Many smoking cessation interventions include physical activi…
Posted May 21, 2026
Precision Therapy to Target Pancreatic Ductal Adenocarcinoma
US National Cancer Institute · grant
GOAL A (completed)- MSLN is the target of many therapeutics being tested in clinical trials but little is understood about the effect of MSLN on PDAC aggressiveness and therapeutic resistance. We have previously found that loss of MSLN impa…
Posted May 21, 2026
Clinical Support
US National Cancer Institute · grant
I have participated as a Medical Oncology consultant for the NINDS team studying novel pain therapeutic RTX. I continue to support the Surgical Oncology program by providing Medical Oncology advice at the GI Tumor Board. I continue to teach…
Posted May 21, 2026
First in Human Trials of ProAgio, a Cytotoxin
US National Cancer Institute · grant
Enrollment to the ProAgio study was completed this year and data are currently under analysis, including scientific correlatives being performed on patient samples. We have identified a safe dose of ProAgio to give to patients and found tha…
Posted May 21, 2026
Rare Exocrine Tumors of the Pancreas
US National Cancer Institute · grant
During this past year, we completed accrual to Phase 2 study of Minnelide for ASCP and began correlative science on samples associated with the study. Study results were presented at AACR Annual meeting and a manuscript is in preparation. I…
Posted May 21, 2026
The role of microglia in TRPV4 mediated neurodegeneration
US National Institute of Neurological Disorders and Stroke · grant
Project Summary/Abstract Microglia play diverse roles in neurodegenerative disorders such as Alzheimer’s disease, multiple sclerosis, and the motor neuron diseases amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). Recen…
Posted May 21, 2026
Postdoctoral Training Program in Alcohol Studies
US National Institute on Alcohol Abuse and Alcoholism · grant
This renewal application is for five years of continued support of the Postdoctoral Training Program in Alcohol Studies at the University of Connecticut School of Medicine (UConn Health). The program was established in 1980 and evolves with…
Posted May 21, 2026
A Mixed-Methods Study of the Social Ecological and Integration Factors Associated with HIV Prevention Behaviors Among Latino/x Sexual Minority Migrant Men in the U.S.
US National Institute on Minority Health and Health Disparities · grant
Project Summary HIV remains the most pressing public health issue for Latino/x sexual minority men (SMM) in the U.S. Although Latino/x SMM comprise a small percentage of the U.S. population, they make up a majority of new HIV infections. To…
Posted May 21, 2026
Addressing insufficient positive airway pressure use among older Veterans with obstructive sleep apnea
US Veterans Affairs · grant
Background: The most frequently diagnosed sleep disorder among older Veterans is obstructive sleep apnea (OSA), which is associated with serious adverse effects on health, quality of life and survival. Positive airway pressure (PAP) is reco…
Posted May 21, 2026
Epigenetic regulation of intestinal tuft cells
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
Intestinal epithelial cells reside at the direct interface between the microbiota and mammalian host, and are thus uniquely poised to sense microbial signals that calibrate intestinal immunity and function. Tuft cells are a specialized epit…
Posted May 21, 2026
Host integration of commensal and pathogenic bacterial-derived signals
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
PROJECT SUMMARY Enteric bacterial infections remain one of the greatest public health challenges worldwide and deciphering the mechanisms that protect against infection will enable development of new treatments. Intestinal tissues are in co…
Posted May 21, 2026
Gene Therapy for LCA5-Assocated Inherited Retinal Degeneration: Extension to Pediatric Cohorts
US Food and Drug Administration · grant
PROJECT SUMMARY / ABSTRACT Advances in genetics and genomics have raised hopes for the development of gene-based treatments for inherited retinal diseases (IRDs) which are single-gene defects that cause vision loss. Some of the greatest suc…
Posted May 21, 2026
Human Tissues, Lipidomics, and Proteomics Core
US National Heart Lung and Blood Institute · grant
SUMMARY – HUMAN TISSUES, LIPOPROTEINS, LIPIDOMICS, & PROTEOMICS CORE (C2) The Human Tissues, Lipoproteins, Lipidomics, and Proteomics Core (Core 2, C2) will focus on providing human tissues and analytical capabilities to all three projects …
Posted May 21, 2026
Assessing TGF Beta1-Mediated ECM Remodeling in Metastatic Oral Squamous Cell Carcinoma
US National Institute of Dental and Craniofacial Research · grant
Abstract Oral squamous cell carcinoma (OSCC) patients have a dismal survival rate due to distant metastases that escape primary care. Transforming growth factor beta (TGFβ) is a well-known driver of metastasis, modulator of immune cell acti…
Posted May 21, 2026
Positioning Mason's Regional Biocontainment Laboratory for Effective Pandemic Preparedness
US National Institute of Allergy and Infectious Diseases · grant
OVERALL CORE ABSTRACT George Mason University (GMU) Biomedical Laboratory (BRL) is one of 12 Regional Biocontainment Laboratories (RBLs) established through NIAID support in the early 2000s to serve as Biosafety Level 3 (BSL-3) facilities t…
Posted May 21, 2026